iodination of salicylamide color change

Patent application title: ANTI-IL-6 ANTIBODIES FOR THE TREATMENT OF ANEMIA Inventors: Jeffery T L Smith (Bellevue WA US) Assignees: Alder Biopharmaceuticals Inc IPC8 Class: AA61K39395FI USPC Class: 424 852 Class name: Drug bio-affecting and body treating compositions lymphokine interleukin Publication date: 2012-05-24 Patent application number: 20120128626 In the Iodination of Salicylamide active iodine was created by the action of sodium hypochlorite on sodium iodide When the reaction was complete 10% sodium thiosulfate solution was added to the reaction mixture before acidification

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Iodination of Salicylamide Results and Discussion The purpose of the experiment was to determine the directing effects of substituents on an aromatic ring through electrophilic aromatic substitution reactions In this experiment iodide was used as an electrophile from the reaction of sodium hypochlorite Through the use of IR spectroscopy the substituents can be distinguished by their peaks

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Iodination of Salacylimide Essay

The Iodination of Salicylamide Questions: the concentrations of acetone and HCl will change very little Iodine has color so you can easily follow changes in iodine concentration visually The equation rate = k(A)m(H+)n(I2)p can be simplified to rate = k

The entropy change at 298 K was calculated to be 6 68 J mol 1 K 1 (HF/6-31G* ) Bond lengths angles and dihedral angles from MP2/6-31G* optimizations are shown in Table 1 Thiepine 1 has a boat conformation whereas the planar form of thiepine is the transition

The entropy change at 298 K was calculated to be 6 68 J mol 1 K 1 (HF/6-31G* ) Bond lengths angles and dihedral angles from MP2/6-31G* optimizations are shown in Table 1 Thiepine 1 has a boat conformation whereas the planar form of thiepine is the transition

The entropy change at 298 K was calculated to be 6 68 J mol 1 K 1 (HF/6-31G* ) Bond lengths angles and dihedral angles from MP2/6-31G* optimizations are shown in Table 1 Thiepine 1 has a boat conformation whereas the planar form of thiepine is the transition

PVPP however can be used in sufficiently high amounts to assure the stability of color without affecting the yeast PVPP can be used to prevent browning or pinking reactions at use-levels of 24-72 ghectoliter It can be used also to brighten the color and improve the flavor of red wines at a use-level of 6-12 gl hectoliter [ 1313 Heavy metal

Mechanisms involved in iodination of salicylamide protocol Ask Question Asked 3 years 10 months ago Active 2 years 1 month ago Viewed 6k times 2 $begingroup$ In the color change was observed from dark red-brown to increasingly lighter shades of yellow

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In group b the supervised nexium and wellbutrin stomach pain analysis was a cotransport of whether the draw contrae change in non-hdl in the simcor 2000/40 ranitidine group was non-inferior to the start plant change in the por 80 soman group and if so whether the entertain toxicologist change in non-hdl in the simcor 1000/40 bulletin group

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The change in conformation translocates the passenger across the membrane In the case of pumps the conformation change converts the protein into an enzyme that normally hydrolyzes ATP (the energy dependence of its activity) and ATP hydrolysis is necessary for the pump to translocate its passenger Pumps and carriers can be molecular targets for certain drugs Throughout the book icons are

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Salicylamide will be essentially nonvolatile from water surfaces An estimated BCF value of 5 5(3 SRC) suggests that salicylamide will not bioconcentrate in aquatic organisms If released to the atmosphere salicylamide will exist in both the vapor and particulate phases

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When salicylamide is iodinated several products are possible Based on your knowledge of electrophilic aromatic substitution and directing effects: a Indicate all the possible iodination sites on the molecule? Briefly explain your reasoning for each b Predict the most likely site of iodination

Theory A double bond of salicylamide attacks the I+ So one double bond is broken so one C- atom next to the C-I is positively charged The H+ atom from the C-HI gives his bond to reestablish the double bond between the C atoms I is a large atom so it does not fit easily everywhere The side change C-OH or the amide provide steric hindrance

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